Nature, Published online: 18 September 2024; doi:10.1038/d41586-024-03015-y

Differences in gene expression between individuals are an important source of variation in traits and diseases. However, most of the research into such differences in humans has focused on individuals of European ancestries, limiting its generalizability. A geographically diverse, open-access gene-expression resource now enables the exploration of variation of gene expression in under-represented populations.