Lineage tracing of stem cells decades after blood and bone-marrow transplantation

by | Feb 5, 2025 | Uncategorized | 0 comments

Author

Nature, Published online: 05 February 2025; doi:10.1038/d41586-025-00345-3

In individuals receiving an allogeneic haematopoietic cell transplant, stem cells in the bone marrow, which give rise to blood and immune cells, are replaced with those from a donor. Genome-sequencing analyses in donor–recipient pairs years after transplantation show an accelerated loss of clonal diversity in the blood stem cells of recipients compared with those of donors.

Archive Posts

0 Comments

Submit a Comment

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.